Artificial intelligence is fundamentally transforming the e-commerce landscape, reshaping how consumers discover, evaluate, and purchase products online. AI-powered search engines and shopping assistants like Perplexity, ChatGPT, and Amazon Rufus are shifting the paradigm from traditional keyword-based search to intent-driven, conversational experiences. This transformation affects every major e-commerce stakeholder—brands, retailers, marketplaces, publishers, advertisers, affiliates, and marketers. Organizations that fail to optimize for AI discovery and engagement risk becoming invisible in an increasingly AI-mediated environment, with research from Accenture showing that a substantial majority of consumers now expect personalized shopping experiences. IDC projects that global AI spending across industries will reach $154 billion in 2023, with retail representing one of the fastest-growing sectors. This white paper provides a strategic roadmap for AI integration and highlights the new executive competencies required to navigate this revolution successfully.